Down Syndrome

CIIT

Sameen Noushad

2014

GENETICS ASSIGNMENT

DOWN SYNDROME

CIIT

Sameen Noushad

2014

GENETICS ASSIGNMENT

DOWN SYNDROME

Table of Contents

INTRODUCTION 2

GENETICS OF DOWN SYNDROME: 3

SYMPTOMS 4

Physical 4

Neurological 5

Senses 5

Heart 6

Cancer 6

Fertility 6

Prognosis for People with Down syndrome 7

Life of Adults: 7

Life of Children: 7

Management for People with Down syndrome 8

Health Screening: 8

Cognitive development: 8

Drugs and Supplements: 9

References: 10

DOWN SYNDROME

DOWN SYNDROME

INTRODUCTION

Down syndrome is a chromosomal disorder caused by a fault in cell division; the outcome of which is an extra 21st chromosome. The condition leads to impairments in both mental capability and physical development ranging from mild to moderate levels. After series of screenings and tests, Down syndrome can be detected before and after birth. The only factor known to affect the likelihood of having a baby with Down syndrome is maternal age. That is, less than one in 1,000 pregnancies for mothers less than 30 years of age results in a baby with Down syndrome. For mommies who are 44 years of age, about 1 in 35 pregnancies results in a baby with Down syndrome. Because younger ladies generally have more children, 75 - 80% of children with the disorder are born to younger women. (http://www.medicalnewstoday.com/articles/145554.php)

(Agathokleous et.al ,2013)

(Verweij, EJ et.al, 2012)

GENETICS OF DOWN SYNDROME:

Down syndrome results when one of three types of abnormal cell division involving chromosome 21 occurs. All three cell division abnormalities result in extra genetic material from chromosome 21, which is responsible for the characteristic features and developmental problems of Down syndrome. The three genetic variations that can cause Down syndrome include: (http://www.mayoclinic.org/diseases-conditions/down-syndrome/basics/causes/con-20020948)

SYMPTOMS

Physical

Those with Down syndrome nearly always have physical and intellectual...