Submitted by: Submitted by mojamoja
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Category: Science and Technology
Date Submitted: 08/20/2011 04:22 AM
Thromboangiitis Obliterans (Buerger’s Disease)
* Recurring inflammation of the small and medium-sized arteries and veins of the upper and lower extremities that results in thrombus formation and occlusion of vessels
* Incidence and etiology
* Most often in men between 20 and 40 yrs old
* Risk factors: family history of disease, cigarette smoking
* Clinical Manifestations
* Small and medium-sized arteries and veins are affected in a segmental fashion
* Acute lesions form with proliferation of the intima and thrombosis
* In later stages, lesions become less cellular and turn into a dense scar
* Commonly, lesions of varying stages of progression can be seen in the same vessel
* Pain, most common symptom, present in 1 or more digits
* Superficial thrombophlebitis is commonly seen in affected extremity before arterial symptoms appear
* Pain is accompanied by signs of ischemia (color or temperature changes)
* Numbness and tingling of extremities is a result of ischemic neuropathy
* Occlusion of distal arteries of the upper and lower extremities develop spontaneously or as result of trauma
* Secondary infection of the ulcer sire with partial amputation is unusual
* Edema of the foot is common
* Pulses in distal limbs (radial, ulnar, dorsalis pedis, posterior tibial arteries)are diminished or absent
* Diagnostics:
* Arteriography/angiography: a technique injecting of contrast media into the vascular system to outline the heart and blood vessels. It become selective arteriography / angiography when a particular heart chamber or blood vessel is singled out for study. It makes use of cineangiograms, a series of rapidly changing films or movies on an intensified fluoroscopic screen that records the passage of the contrast medium through the vascular site(s). Common selective angiography sites: aorta, coronary arteries,...