Pharm

PHARMACOLGY INTRODUCTION

Study of therapeutic agents

Pharmacology- science that deals with study of therapeutic agents

Pharmacokinetics- what body does to drug

Administration=when drug is given

Absorption=when drug is taken by body

Distribution=when drug spreads through body

Metabolism & Excretion=when drug is removed by body

Pharmacodynamics- what drug does to body; drug/receptor interaction

Pharmacotherapeutics- study of use of drugs in treatment of disease; drug effect or response

Pharmacocognosy- identifying crude materials as drugs; source of drugs

Animals, plants, minerals, synthetic; microbes

Foxglove plant=digitalis used for CHF

Beef/pork pancreas=insulin for diabetes

Ephedra=ephedrine for respiratory ailments

Yams=estrogen hormone replacement therapy

Belladonna plant=source of atropine to dilate pupils

Meadow flower-colchicines=gout

Toxicology- study of harmful effects of drugs on living tissues; any drug not given in proper dose can be toxic; even acetimophen (Tylenol) can cause hepatocellular liver necrosis ( prolonged use

• NSAIDs ( don’t take without a prescription b/c can cause tubular necrosis (tubule that transfers urine to ureters)

• Prolonged use of pain killer can kill you

• Drugs can’t take during pregnancy

1. tetracycline- antibiotic used to treat infections comes from the genus streptomyces

2. Streptomycin- an antibiotic produced by the actinomycete Streptomyces griseus and used to treat tuberculosis

Pharmacy-science of preparing and dispensing medication

Posology-study of amount of drug required to produce therapeutic effects

• Drug should reach the brain (target site)

• Sometimes 70% can be loss and only 30% reaches the target site ( therefore it is important to know the correct dose in order for the drug to reach the target site

• Drugs are usually metabolized in the liver and kidneys most are completely excreted from the...