Keeping Up with the Joneses

Unit 10: Keeping Up With the Jones’s Case Study

Part I:

1. What two parameters are responsible for creating the movement (filtration and reabsorption) of fluid across the capillary wall?

The blood pressure (hydrostatic pressure) and water pressure (osmotic pressure) are responsible for creating and balancing the movement of fluid across the capillary wall.

2. Find a diagram of a capillary – copy/paste and cite the source.

[pic]

http://www.biog1105-1106.org/demos/105/unit7/fluidexchange.html

3. Under normal circumstances, what components of the blood cross the capillary wall?

Interstitial fluid travels across capillary walls. Water and other small solutes can also diffuse across the capillary walls but blood cells cannot.

4. Cytokines, like histamine and leukotrienes, are secreted by damaged cells in Dave’s ankle. How do these cytokines cause inflammation?

Secreted cytokine proteins provide signals between immune cells to coordinate the inflammatory response.

5. How does the application of ice to the ankle affect blood flow through the capillaries?

The application of ice to the ankle causes the capillaries to constrict. This decreases the blood flow to the ankle and reduces swelling.

6. How does the removal of ice from the ankle affect blood flow through the capillaries and the cytokines?

The removal of ice on the ankle will return the blood flow and cytokines to normal, therefore, blood flow will increase.

7. How does compression, which is provided by an elastic (Ace) bandage wrapped around the damaged ankle, decrease inflammation?

An ace bandage will physically constrict the blood vessels of the ankle causing a reduction in inflammation.

8. How does elevation of the damaged ankle decrease inflammation?

When the ankle is elevated, the blood flow to the heart increases. This would decrease the blood flow to the leg and cause the swelling to lessen.

Part II:

1. What problems are there in...