Submitted by: Submitted by P4percamper
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Date Submitted: 03/05/2014 07:25 AM
ABSTRACT
Background: Skeletal muscle (SM) is a large body compartment
of biological importance, but it remains difficult to quantify SM
with affordable and practical methods that can be applied in clinical
and field settings.
Objective: The objective of this study was to develop and
cross-validate anthropometric SM mass prediction models in
healthy adults.
Design: SM mass, measured by using whole-body multislice
magnetic resonance imaging, was set as the dependent variable
in prediction models. Independent variables were organized into
2 separate formulas. One formula included mainly limb circumferences
and skinfold thicknesses [model 1: height (in m) and
skinfold-corrected upperarm, thigh, and calf girths (CAG, CTG,
and CCG, respectively; in cm)]. The other formula included
mainly body weight (in kg) and height (model 2). The models
were developed and cross-validated in nonobese adults [body
mass index (in kg/m2) < 30].
Results: Two SM (in kg) models for nonobese subjects (n = 244)
were developed as follows: SM = Ht (0.00744 CAG2 +
0.00088 CTG2 + 0.00441 CCG2) + 2.4 sex 0.048 age
+ race + 7.8, where R2 = 0.91, P < 0.0001, and SEE = 2.2 kg;
sex = 0 for female and 1 for male, race = 2.0 for Asian, 1.1 for
African American, and 0 for white and Hispanic, and SM = 0.244
BW + 7.80 Ht + 6.6 sex 0.098 age + race 3.3,
where R2 = 0.86, P < 0.0001, and SEE = 2.8 kg; sex = 0 for female
and 1 for male, race = 1.2 for Asian, 1.4 for African American,
and 0 for white and Hispanic.
Conclusion: These 2 anthropometric prediction models, the first
developed in vivo by using state-of-the-art body-composition
methods, are likely to prove useful in clinical evaluations and
field studies of SM mass in nonobese adults. Am J Clin Nutr
2000;72:796–803.
KEY WORDS Limb circumference, skinfold thickness,
body composition, skeletal muscle, nonobese adults
INTRODUCTION
Although skeletal muscle (SM) makes up the largest fraction
of...