Chest Journal Iron Lung

4/22/2014

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American College of Chest Physicians

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January 2002, Vol 121, No. 1

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Clinical Investigations in Critical Care | January 2002

Iron Lung vs Mask Ventilation in the Treatment of Acute on Chronic Respiratory Failure in COPD Patients*:

A Multicenter Study

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Antonio Corrado, MD, FCCP; Marco Confalonieri, MD; Santino Marchese, MD; Corrado Mollica, MD; Giuseppe Villella, MD; Massimo Gorini, MD; Rossana Della Porta, MD

Author and Funding Information Chest. 2002;121(1):189-195. doi:10.1378/chest.121.1.189 Article Tables References Text Size:

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Web of Science® Times Cited: 18

Abstract

Abstract | Materials and Methods | Results | Discussion | References

CHEST Journal Articles

Study objectives: Evaluation of the effectiveness of negative-pressure ventilation (NPV) with the use of the iron lung vs noninvasive positive-pressure ventilation (NIPPV) in the treatment of COPD patients with acute on chronic respiratory failure. Design: A retrospective case-control study. Setting: Four Italian respiratory intermediate ICUs. Patients: Of a total of 393 COPD patients admitted to the ICU in 1996, 53 pairs were treated with the iron lung (NPV group). Patients treated with NIPPV (NIPPV group) were matched according to mean (± SD) age (70.3 ± 7.1 vs 70.3 ± 6.9 years, respectively), sex, causes of acute respiratory failure (ARF), APACHE (acute physiology and chronic health evaluation) II score (22.4 ± 5.3 vs 22.1 ± 4.6, respectively), pH (7.26...