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Date Submitted: 05/04/2014 10:35 PM
Lecture 20- Regenerative Medicine
* Growing cells and tissues that can be used to ____________________________________________ and organs
* Using stem cells
Tissue Regenerative Medicine
* The end goal:
* To create products ______________________________ or heal tissue defects.
* Replace diseased or damaged tissue
* Because……
* Donor tissues and organs are in __________________________
* We want to _________________________________ response by using our own cells or novel ways to protect transplant.
* Regenerate, repair and replace
* ________________________________
* Identify the cues that allow for regeneration without _______________________
* Like growing a new limb
* _____________________________
* Stimulate the tissue at a cell or molecular level, even at level of DNA, to repair itself.
* Replace
* A biological __________________________________ in the lab that can be implanted to replace the tissue or organ of interest
* Tissue-engineered products contain mixtures of the following:
* Biological components _________________________
* Can be genetically modified to behave a specific way
* Chemicals
* that tell the tissue to _____________________________
* A non-biological component
* ______________________________________
* Fibers, plastic, other natural components
* Gels
Scaffolds
* Various textures and materials
* Encourage ________________________________
* Allow nutrients to ___________________________
* Won’t___________________ the patient
* Transplants that match the patient
* Remove cells ________________________
* Grow in culture with or without biomaterials
* Give appropriate chemicals to make cells do ____________________________
* Replace into patient
A new bladder
* To make a bladder one need a scaffold and several ___________________________
Bone repair
* Obtain...