Dna Sequence Analysis and Error Correction

DNA Sequence Analyses and Error Correction: A Major Qualifying Project A Term Major Qualifying Project Report Submitted to the faculty of WORCESTER POLYTECHNIC INSTITUTE

Advisors: Professor Patrick Flaherty

Submitted By: Wai Phyo Maung Maris Pepo Jared Erb Alec Rebh

Date: Thursday, April 30, 2014

TABLE OF CONTENT

AUTHORSHIP .......................................................................................................................................... 4 ACKNOWLEDGEMENTS........................................................................................................................ 5 ABSTRACT ................................................................................................................................................ 6 CHAPTER 1-INTRODUCTION ............................................................................................................. 7 CHAPTER 2-LITERATURE REVIEW ................................................................................................ 10

2.1 Illumina Background ............................................................................................................................. 10 2.2 Information on the freeIbis ................................................................................................................... 12 2.3 Real World Application ......................................................................................................................... 14 2.4 Problems and issues.............................................................................................................................. 15

CHAPTER 3-PROJECT STRATEGY ................................................................................................... 18 CHAPTER 4-ALTERNATIVE DESIGNS ............................................................................................ 25

4.1 Needs Analysis...