Genome-Wide Meta-Analysis Identifies Six Novel Loci Associated with Habitual Coffee Consumption

Molecular Psychiatry (2014), 1–10 © 2014 Macmillan Publishers Limited All rights reserved 1359-4184/14 www.nature.com/mp

ORIGINAL ARTICLE

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

The Coffee and Caffeine Genetics Consortium, MC Cornelis1,2, EM Byrne3,117, T Esko4,5,6,7,117, MA Nalls8,117, A Ganna9, N Paynter10, KL Monda11, N Amin12, K Fischer4, F Renstrom13, JS Ngwa14, V Huikari15, A Cavadino16, IM Nolte17, A Teumer18, K Yu19, P Marques-Vidal20, R Rawal21, A Manichaikul22, MK Wojczynski23, JM Vink24, JH Zhao25, G Burlutsky26, J Lahti27,28, V Mikkilä29,30, RN Lemaitre31, J Eriksson32, SK Musani33, T Tanaka34, F Geller35, J Luan25, J Hui36,37,38,39, R Mägi4, M Dimitriou40, ME Garcia41, W-K Ho42, MJ Wright43, LM Rose10, PKE Magnusson9, NL Pedersen9, D Couper44, BA Oostra45, A Hofman12, MA Ikram12,46,47, HW Tiemeier12,48, AG Uitterlinden12,49, FJA van Rooij12, I Barroso50,51, I Johansson52, L Xue14, M Kaakinen15,53,54, L Milani4, C Power16, H Snieder17, RP Stolk17, SE Baumeister55, R Biffar56, F Gu19, F Bastardot57, Z Kutalik58,59,60, DR Jacobs Jr61, NG Forouhi25, E Mihailov4, L Lind62, C Lindgren63, K Michaëlsson64, A Morris63, M Jensen2, K-T Khaw42, RN Luben42, JJ Wang26, S Männistö65, M-M Perälä65, M Kähönen66, T Lehtimäki67, J Viikari68, D Mozaffarian1,2,69,70, K Mukamal71, BM Psaty31,72,73,74, A Döring75, AC Heath76, GW Montgomery43, N Dahmen77, T Carithers78, KL Tucker79, L Ferrucci34, HA Boyd35, M Melbye35, JL Treur24, D Mellström32, JJ Hottenga24, I Prokopenko63,80, A Tönjes81,82, P Deloukas50,83,84, S Kanoni83, M Lorentzon32, DK Houston85, Y Liu86, J Danesh42, A Rasheed87, MA Mason88, AB Zonderman89, L Franke90, BS Kristal91,92, International Parkinson's Disease Genomics Consortium (IPDGC)118, North American Brain Expression Consortium (NABEC)118, UK Brain Expression Consortium (UKBEC)118, J Karjalainen90, DR Reed93, H-J Westra90, MK Evans88, D Saleheen42,87, TB Harris41, G Dedoussis40, G Curhan1, M...