Fragment-Based Drug Discovery Market Expected to Reach Usd 1.2 Billion Globally in 2023

The assurance of logical and efficient lead innovation has fuelled interest for fragment-based drug discovery (FBDD). This enthusiasm is further complemented by a paradigm shift from conventional techniques like high-throughput screening (HTS) towards design intensive approaches, enabled

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Choose file by computational and structural biology. Fragment-based drug discovery utilizes comparatively small libraries of “fragments or ligands” that are of low-molecular weights. These fragments are evaluated for binding affinity, then incrementally altered into more potent molecules against the biological target(s) of interest. The major advantages of this technique that are expected to drive the popularity of FBDD among pharmaceutical companies are less cost and time process, streamlined equipment operability, and higher success rates of hits.

Major factors likely to boost the growth of the market are Simpler and less time consuming technique, streamlining and easy access to advanced biophysical techniques could drive the market in the near future. However, lower level of potency in few of the compounds derived from fragment screening and requirement of high protein and unique fragment library to conduct studies would hamper the growth of the fragment-based drug discovery market during the forecast period.

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Fragment screening services and fragment optimization collectively form the fragment-based drug discovery market. Fragment screening segment was further segmented into biophysical services and non-biophysical services. Biophysical services are further segmented into techniques such as Nuclear Magnetic Resonance (NMR) Spectroscopy, Differential scanning Fluorimetry (DSF) Assay (Thermal Shift), Fluorescence Polarization (FP), Isothermal Titration Calorimetry (ITC), X-ray Crystallography, Surface Plasmon...