Synopses: House "Dont Ever Change"

Roz is a Hasidic Jew, recently converted, and even more recently married. At her wedding ceremony, she loses control of her bladder, and a large stain of bloody urine appears. She collapses and falls, breaking her leg. She is admitted to House’s team for the evaluation of her condition. Dr. Thirteen reports that Roz’s urine culture was negative and there is no history of trauma or sexually transmitted diseases. A CT scan was negative for cancer and kidney stones. She reports that Roz’s sodium was low and suggests that Roz may have endometriosis of the bladder. Taub says that the low sodium may be related to Roz fasting before the wedding, while House argues that Roz may have been exposed to a toxin called carboxylic acid. House agrees to let Thirteen start Roz on treatment for the possible endometriosis and get a cystoscopy . Meanwhile, he sends Taub and Foreman to search Roz’s apartment where they find no carboxylic acid, but discover that she had been a heavy metal record producer. She admits to a history of heroin use, but not for 6 months. They take a hair sample, but the tests are negative. The treatment for endometriosis has been unsuccessful and the cystoscopy was clean.

Taub suggests Roz may have cryoglubulinemia but House feels she has porphyria , and her sudden conversion to Judaism suggests the mental problems commonly seen in certain types of porphyria. Roz’s husband takes this as an insult, and requests a new doctor. Cuddy agrees with the cryoglobulinemia diagnosis and wants to start her on Indomethacin. Meanwhile, Roz has become hypoxic with her oxygen saturation dropping to 85%. This argues against both cryoglobulinemia and porphyria. She is kept on oxygen and her saturation improves. Foreman mentions Wegener’s Granulomatosis, but House now believes that it is Lupus with a hidden heart problem. He orders a stress test. Roz makes it through the test and has no evidence of heart problems. After the test, she develops sudden leg pain and the team...