Learning Objectives Human Physiology Study Guide

6. Chapter 3, Membranes and membrane function

A. Membrane structure

1. You should be able to define integral, hydrophilic, hydrophobic, integral protein, transmembranal protein, peripheral protein, glycoprotein, antigen, histocompatibility antigen.

2. You should be able to discuss the fluid mosaic model of membrane structure.

The structure of biological membranes consists of various proteins that are attached to or embedded in a bilayer of amphipathic phospholipids

3. You should be able to reproduce and label a diagram of a typical animal cell membrane.

4. You should be able to identify which parts of the membrane are hydrophilic/polar and hydrophobic/non-polar.

5. You should You should be able to differentiate between peripheral, integral and transmembranal proteins.

Peripheral: Provides the framework for the plasma membrane and is attached to integral protein.

Integral: Go through the membrane with two hydrophilic ends.

Transmembrane: these proteins span the distance from the outside to the inside of the cell

6. You should be able to explain the importance of cholesterol in membrane structure.

Cholesterol's role in cell membrane function helps to keep this lining intact and assists with moving needed nutrients in and out of the cell.

IT CONTRIBUTES TO BOTH THE FLUIDITY AND THE STABILITY OF THE MEMBRANE

7. You should be able to name some functions of membrane proteins and glycoproteins.

MEMBRANE PROTEINS: some form channels( water filled pathways)

Carrier or transport

Membrane bound enzymes

Recognition proteins

Receptors, and docking marker acceptors

GLYCOPROTEINS: Hold cells together

Form tight junctions

8. You should be able to draw a representation of a tight junction, a desmosome (adherence) junction and a gap (communication junction.

9. You should be able to explain the functions of the different membrane junctions and give an example of where these junctions might be found.

Desmosomes (adhering...