Yeast

1. 4-5 questions from text book chapter 8

2. be familiar with the handouts, characteristics of malignant tumor cells, malignant versus benign

3. carcinogenic multi step process, term used to describe the process, sections with initiation, promotion.. etc

4. idea of multi step process and the process that leads towards maglignancy

5. term carcinoma

6. know difference between initiation and promotion

7. criteria--- that may serve as evidence as chemical carcinogenesitity

a. in PP, related to controls

8. know what is meant by genotoxic, what characterizes those substances

9. be familiar with aplasia, hypoplasia, atrophy, dysplasia

10. chemical carcinogen—be aware of the fact that they are the development of canncer, usually the result of what type of event—mutation event

11. know what a pro carcinogen (pre carcinogen) is

12. know what a co carcinogen is

13. there are a number of problems associated with environmental agents linked to human tumors--- listed in PP (ex- moving targets-chemical may not be a carcinogen until consumed and is then transformed into a carcinogen making it a moving target)

14. dealing with mutations – chapter 9 (3-4 book)

15. the fact the carcinogen is a result of a mutengic effect, not all mutegins are carcinogens

16. dominant lethal test, what is it

b. deals with mutagenicity

c. looking at the male

17. point mutations

d. base pair, ames test

18. chapter 10---(3-4 book)

19. period during pregnancy where teratogenic effects are possible

e. remember the time of exposure and also the dose

20. FDA guidelines – phase 1,2,3 what each phase measures or analyzes

21. Pesticides, chapter 22 (2-3 book)

22. Be familiar with type of toxin that is produced by puffer fish and what is blocks with neurological effects

23. Be familiar with the term Asphyxial droxia

24. Atropine, what Is it used for, what type of effect...