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Unit 4 Lecture Study Guide
Use the lecture folder to help you complete this guide. The more detail you can provide the better prepared for the test you will be.
What is the integumentary system and its primary characteristics? Integumentary system is the skin and its derivatives, who protect external protection for the body. Primary characteristics: covers the entire body, accounts for about 7% of the total body weight, pliable(yet durable), thickness:1.5 to 4.0 mm, and is composed of the epidermis and dermis
Describe and give at least one example of each of the functions of the integumentary system. Protection
Chemical Barriers (skin secretion and melanin), Skin secretions (acid mantle)
Low pH and sebum slow bacterial growth on skin surface
Human defensin – natural antibiotic
Cathelicidins – proteins that prevent Strep A infection in wounded skin
Melanin – chemical pigment that prevents UV damage
Physical/Mechanical Barriers – continuity of the skin and hardness of keratinized cells
Continuity prevents bacterial invasion
Glycolipids prevent diffusion of water and water-soluble substances between cells
Substances that are able to penetrate the skin:
Lipid-soluble substances (i.e., oxygen, carbon dioxide, steroids, and fat-soluble vitamins)
Oleoresins of certain plants (ex. Poison ivy and poison oak)
Organic solvents (ex. Acetone, dry cleaning fluid, and paint thinner)
Salts of heavy metals (ex. Lead, mercury, and nickel)
Penetration enhancers
Biological Barriers – Langerhans’ cells, macrophages, and DNA
Langerhans’ cells in epidermis present antigens to lymphocytes
Dermal macrophages (2nd line of defense) – attack bacteria and viruses that have penetrated the epidermis
DNA structure – the electrons in DNA absorb UV radiation and converts it to heat
Body Temperature Regulation
Production of copious amounts of sweat to dissipate heat
Constriction of dermal blood vessels to retain heat
Cutaneous Sensation – cutaneous...